Sudden Death in Obesity: Mechanisms and Management
Holmstrom, Lauri; Junttila, Juhani; Chugh, Sumeet S (2024-11-06)
Avaa tiedosto
Sisältö avataan julkiseksi: 06.11.2025
Holmstrom, Lauri
Junttila, Juhani
Chugh, Sumeet S
Elsevier
06.11.2024
Holmstrom, L., Junttila, J., & Chugh, S. S. (2024). Sudden death in obesity. Journal of the American College of Cardiology, 84(23), 2308–2324. https://doi.org/10.1016/j.jacc.2024.09.016
https://creativecommons.org/licenses/by-nc-nd/4.0/
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
https://creativecommons.org/licenses/by-nc-nd/4.0/
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
https://creativecommons.org/licenses/by-nc-nd/4.0/
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:oulu-202502171718
https://urn.fi/URN:NBN:fi:oulu-202502171718
Tiivistelmä
Abstract
In recent decades, the prevalence of obesity has increased significantly, leading to an epidemic at the global level. Obesity is associated with various metabolic alterations and increases the risk of cardiovascular disease. The most devastating manifestation of cardiovascular disease is sudden cardiac death (SCD), leading to substantial years of potential life lost worldwide. Obesity-related SCD is an increasingly important public health problem and warrants a specific investigative focus on improved risk stratification and prevention. In this review, we summarize the current evidence regarding management of SCD in obesity and discuss knowledge gaps as well as future directions in this field.
In recent decades, the prevalence of obesity has increased significantly, leading to an epidemic at the global level. Obesity is associated with various metabolic alterations and increases the risk of cardiovascular disease. The most devastating manifestation of cardiovascular disease is sudden cardiac death (SCD), leading to substantial years of potential life lost worldwide. Obesity-related SCD is an increasingly important public health problem and warrants a specific investigative focus on improved risk stratification and prevention. In this review, we summarize the current evidence regarding management of SCD in obesity and discuss knowledge gaps as well as future directions in this field.
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