Effects of Illumination Angle and Different Light Sources on Acousto-Optic-based Sensing of Focused Ultrasound
Omidali, Mohammadreza; Rahayu, Triana; Zhao, Zuomin; Moradi, Sadegh; Myllylä, Teemu (2024-12-05)
05.12.2024
Omidali, M., Rahayu, T., Zhao, Z., Moradi, S., & Myllylä, T. (2024). Effects of illumination angle and different light sources on acousto-optic-based sensing of focused ultrasound. Journal of Biomedical Photonics & Engineering, 10(4), 040313. https://doi.org/10.18287/JBPE24.10.040313
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© Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
https://creativecommons.org/licenses/by/4.0/
© Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
https://creativecommons.org/licenses/by/4.0/
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:oulu-202412197471
https://urn.fi/URN:NBN:fi:oulu-202412197471
Tiivistelmä
Abstract
The acousto-optic (AO) effect, characterized by the deflection and modulation of photons by ultrasound, is currently being explored to a certain degree. AO could bring together advantages of optics and acoustics particularly addressing the challenges of spatially accurate deep tissue optical sensing that arise from light scattering. Moreover, AO-based monitoring technique could offer valuable insights into the effects of focused ultrasound (FUS) in its therapeutic applications. This paper investigates different light sources (coherents and noncoherent) for use in AO. In particular, we compare tagging efficiency detected in the context of AO signal amplitude. Additionally, the impact of adjusting the angle of the light source to optimize light penetration into the focal area is examined. Experiments were performed in both transmission and reflection modes utilizing AO phantom models, with a primary emphasis on reflection mode. The findings reveal that coherent light sources produce larger but has greater standard deviation in AO signal, while light emitting diodes (LED) yield comparatively stable signals. Additionally, results from reflection mode experiments indicate an enhancement of AO signals by as much as 40% when the angle of coherent sources is adjusted from perpendicular to 45° within a phantom that simulates the optical characteristics of the average human brain.
The acousto-optic (AO) effect, characterized by the deflection and modulation of photons by ultrasound, is currently being explored to a certain degree. AO could bring together advantages of optics and acoustics particularly addressing the challenges of spatially accurate deep tissue optical sensing that arise from light scattering. Moreover, AO-based monitoring technique could offer valuable insights into the effects of focused ultrasound (FUS) in its therapeutic applications. This paper investigates different light sources (coherents and noncoherent) for use in AO. In particular, we compare tagging efficiency detected in the context of AO signal amplitude. Additionally, the impact of adjusting the angle of the light source to optimize light penetration into the focal area is examined. Experiments were performed in both transmission and reflection modes utilizing AO phantom models, with a primary emphasis on reflection mode. The findings reveal that coherent light sources produce larger but has greater standard deviation in AO signal, while light emitting diodes (LED) yield comparatively stable signals. Additionally, results from reflection mode experiments indicate an enhancement of AO signals by as much as 40% when the angle of coherent sources is adjusted from perpendicular to 45° within a phantom that simulates the optical characteristics of the average human brain.
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