The future of integrated structural biology
Schwalbe, Harald; Audergon, Pauline; Haley, Natalie; Amaro, Claudia Alen; Agirre, Jon; Baldus, Marc; Banci, Lucia; Baumeister, Wolfgang; Blackledge, Martin; Carazo, Jose Maria; Carugo, Kristina Djinovic; Celie, Patrick; Felli, Isabella; Hart, Darren J; Hauß, Thomas; Lehtiö, Lari; Lindorff-Larsen, Kresten; Márquez, José; Matagne, André; Pierattelli, Roberta; Rosato, Antonio; Sobott, Frank; Sreeramulu, Sridhar; Steyaert, Jan; Sussman, Joel L; Trantirek, Lukas; Weiss, Manfred S; Wilmanns, Matthias (2024-09-17)
Elsevier
17.09.2024
Schwalbe, H., Audergon, P., Haley, N., Amaro, C. A., Agirre, J., Baldus, M., Banci, L., Baumeister, W., Blackledge, M., Carazo, J. M., Carugo, K. D., Celie, P., Felli, I., Hart, D. J., Hauß, T., Lehtiö, L., Lindorff-Larsen, K., Márquez, J., Matagne, A., … Wilmanns, M. (2024). The future of integrated structural biology. Structure, 32(10), 1563–1580. https://doi.org/10.1016/j.str.2024.08.014
https://creativecommons.org/licenses/by/4.0/
© 2024 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
https://creativecommons.org/licenses/by/4.0/
© 2024 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
https://creativecommons.org/licenses/by/4.0/
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:oulu-202409236002
https://urn.fi/URN:NBN:fi:oulu-202409236002
Tiivistelmä
Summary
Instruct-ERIC, “the European Research Infrastructure Consortium for Structural biology research,” is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users. Here, we describe the current state-of-the-art of integrated structural biology and discuss potential future scientific developments as an impulse for the scientific community, many of which are located in Europe and are associated with Instruct. We reflect on where to focus scientific and technological initiatives within the distributed Instruct research infrastructure. This review does not intend to make recommendations on funding requirements or initiatives directly, neither at the national nor the European level. However, it addresses future challenges and opportunities for the field, and foresees the need for a stronger coordination within the European and international research field of integrated structural biology to be able to respond timely to thematic topics that are often prioritized by calls for funding addressing societal needs.
Instruct-ERIC, “the European Research Infrastructure Consortium for Structural biology research,” is a pan-European distributed research infrastructure making high-end technologies and methods in structural biology available to users. Here, we describe the current state-of-the-art of integrated structural biology and discuss potential future scientific developments as an impulse for the scientific community, many of which are located in Europe and are associated with Instruct. We reflect on where to focus scientific and technological initiatives within the distributed Instruct research infrastructure. This review does not intend to make recommendations on funding requirements or initiatives directly, neither at the national nor the European level. However, it addresses future challenges and opportunities for the field, and foresees the need for a stronger coordination within the European and international research field of integrated structural biology to be able to respond timely to thematic topics that are often prioritized by calls for funding addressing societal needs.
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