Role of gender in short and long-term outcomes after surgery for type a aortic dissection: analysis of a multicentre european registry
Onorati, Francesco; Francica, Alessandra; Demal, Till; Nappi, Francesco; Peterss, Sven; Buech, Joscha; Fiore, Antonio; Folliguet, Thierry; Perrotti, Andrea; Hervé, Amélie; Conradi, Lenard; Dell'Aquila, Angelo M; Rukosujew, Andreas; Pinto, Angel G; Rodriguez Lega, Javier; Pol, Marek; Rocek, Jan; Kacer, Petr; Wisniewski, Konrad; Mazzaro, Enzo; Vendramin, Igor; Piani, Daniela; Ferrante, Luisa; Rinaldi, Mauro; Quintana, Eduard; Pruna-Guillen, Robert; Gerelli, Sebastien; Acharya, Metesh; Mariscalco, Giovanni; Field, Mark; Kuduvalli, Manoj; Pettinari, Matteo; Rosato, Stefano; D'Errigo, Paola; Jormalainen, Mikko; Mustonen, Caius; Mäkikallio, Timo; Di Perna, Dario; Juvonen, Tatu; Gatti, Giuseppe; Battista Luciani, Giovanni; Biancari, Fausto (2024-06-26)
Oxford University Press
26.06.2024
Francesco Onorati, Alessandra Francica, Till Demal, Francesco Nappi, Sven Peterss, Joscha Buech, Antonio Fiore, Thierry Folliguet, Andrea Perrotti, Amélie Hervé, Lenard Conradi, Angelo M Dell’Aquila, Andreas Rukosujew, Angel G Pinto, Javier Rodriguez Lega, Marek Pol, Jan Rocek, Petr Kacer, Konrad Wisniewski, Enzo Mazzaro, Igor Vendramin, Daniela Piani, Luisa Ferrante, Mauro Rinaldi, Eduard Quintana, Robert Pruna-Guillen, Sebastien Gerelli, Metesh Acharya, Giovanni Mariscalco, Mark Field, Manoj Kuduvalli, Matteo Pettinari, Stefano Rosato, Paola D’Errigo, Mikko Jormalainen, Caius Mustonen, Timo Mäkikallio, Dario Di Perna, Tatu Juvonen, Giuseppe Gatti, Giovanni Battista Luciani, Fausto Biancari, Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry, European Journal of Cardio-Thoracic Surgery, Volume 66, Issue 1, July 2024, ezae242, https://doi.org/10.1093/ejcts/ezae242
https://rightsstatements.org/vocab/InC/1.0/
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved. This is a pre-copyedited, author-produced version of an article accepted for publication in European journal of cardio-thoracic surgery following peer review. The version of record Francesco Onorati, Alessandra Francica, Till Demal, Francesco Nappi, Sven Peterss, Joscha Buech, Antonio Fiore, Thierry Folliguet, Andrea Perrotti, Amélie Hervé, Lenard Conradi, Angelo M Dell’Aquila, Andreas Rukosujew, Angel G Pinto, Javier Rodriguez Lega, Marek Pol, Jan Rocek, Petr Kacer, Konrad Wisniewski, Enzo Mazzaro, Igor Vendramin, Daniela Piani, Luisa Ferrante, Mauro Rinaldi, Eduard Quintana, Robert Pruna-Guillen, Sebastien Gerelli, Metesh Acharya, Giovanni Mariscalco, Mark Field, Manoj Kuduvalli, Matteo Pettinari, Stefano Rosato, Paola D’Errigo, Mikko Jormalainen, Caius Mustonen, Timo Mäkikallio, Dario Di Perna, Tatu Juvonen, Giuseppe Gatti, Giovanni Battista Luciani, Fausto Biancari, Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry, European Journal of Cardio-Thoracic Surgery, Volume 66, Issue 1, July 2024, ezae242 is available online at: https://doi.org/10.1093/ejcts/ezae242.
https://rightsstatements.org/vocab/InC/1.0/
© The Author(s) 2024. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved. This is a pre-copyedited, author-produced version of an article accepted for publication in European journal of cardio-thoracic surgery following peer review. The version of record Francesco Onorati, Alessandra Francica, Till Demal, Francesco Nappi, Sven Peterss, Joscha Buech, Antonio Fiore, Thierry Folliguet, Andrea Perrotti, Amélie Hervé, Lenard Conradi, Angelo M Dell’Aquila, Andreas Rukosujew, Angel G Pinto, Javier Rodriguez Lega, Marek Pol, Jan Rocek, Petr Kacer, Konrad Wisniewski, Enzo Mazzaro, Igor Vendramin, Daniela Piani, Luisa Ferrante, Mauro Rinaldi, Eduard Quintana, Robert Pruna-Guillen, Sebastien Gerelli, Metesh Acharya, Giovanni Mariscalco, Mark Field, Manoj Kuduvalli, Matteo Pettinari, Stefano Rosato, Paola D’Errigo, Mikko Jormalainen, Caius Mustonen, Timo Mäkikallio, Dario Di Perna, Tatu Juvonen, Giuseppe Gatti, Giovanni Battista Luciani, Fausto Biancari, Role of gender in short- and long-term outcomes after surgery for type A aortic dissection: analysis of a multicentre European registry, European Journal of Cardio-Thoracic Surgery, Volume 66, Issue 1, July 2024, ezae242 is available online at: https://doi.org/10.1093/ejcts/ezae242.
https://rightsstatements.org/vocab/InC/1.0/
Julkaisun pysyvä osoite on
https://urn.fi/URN:NBN:fi:oulu-202406274985
https://urn.fi/URN:NBN:fi:oulu-202406274985
Tiivistelmä
Abstract
Objectives:
Gender difference in the outcome after type A aortic dissection surgery remains an issue of ongoing debate. In this study we aimed to evaluate the impact of gender on the short- and long-term outcome after surgery for type A aortic dissection.
Methods:
A multicentre European registry retrospectively included all consecutive type A aortic dissection surgery patients between 2005 and 2021 from 18 hospitals across eight European countries. Early and late mortality, and cumulative incidence of aortic reoperation were compared between genders.
Results:
A total of 3902 patients underwent type A aortic dissection surgery, with 1185 (30.4%) being females. After propensity score matching, 766 pairs of males and females were compared. No statistical differences were detected in the early postoperative outcome between genders. Ten-year survival was comparable between genders (47.8% vs 47.1%; Log-rank test, p = 0.679), as well as cumulative incidences of distal or proximal aortic reoperations. Ten-year relative survival compared to country-, year-, age-, and sex-matched general population was higher among males (0.65) compared to females (0.58). The time-period subanalysis revealed advancements in surgical techniques in both genders over the years. However, an increase of stroke was observed over time for both populations, particularly among females.
Conclusion:
The past sixteen years have witnessed marked advancements in surgical techniques for TAAD in both males and females, achieving comparable early and late mortality rates. Despite these findings, late relative survival was still in favour of males.
Objectives:
Gender difference in the outcome after type A aortic dissection surgery remains an issue of ongoing debate. In this study we aimed to evaluate the impact of gender on the short- and long-term outcome after surgery for type A aortic dissection.
Methods:
A multicentre European registry retrospectively included all consecutive type A aortic dissection surgery patients between 2005 and 2021 from 18 hospitals across eight European countries. Early and late mortality, and cumulative incidence of aortic reoperation were compared between genders.
Results:
A total of 3902 patients underwent type A aortic dissection surgery, with 1185 (30.4%) being females. After propensity score matching, 766 pairs of males and females were compared. No statistical differences were detected in the early postoperative outcome between genders. Ten-year survival was comparable between genders (47.8% vs 47.1%; Log-rank test, p = 0.679), as well as cumulative incidences of distal or proximal aortic reoperations. Ten-year relative survival compared to country-, year-, age-, and sex-matched general population was higher among males (0.65) compared to females (0.58). The time-period subanalysis revealed advancements in surgical techniques in both genders over the years. However, an increase of stroke was observed over time for both populations, particularly among females.
Conclusion:
The past sixteen years have witnessed marked advancements in surgical techniques for TAAD in both males and females, achieving comparable early and late mortality rates. Despite these findings, late relative survival was still in favour of males.
Kokoelmat
- Avoin saatavuus [38841]