Autoimmune antibodies to collagen XIII in myasthenia gravis patients
Tu, Hongmin; Pirskanen‐Matell, Ritva; Heikkinen, Anne; Oikarainen, Tuomo; Risteli, Juha; Pihlajaniemi, Taina (2017-09-08)
Tu, H., Pirskanen-Matell, R., Heikkinen, A., Oikarainen, T., Risteli, J. and Pihlajaniemi, T. (2018), Autoimmune antibodies to collagen XIII in myasthenia gravis patients. Muscle Nerve, 57: 506-510. https://doi.org/10.1002/mus.25969
© 2017 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Tu, H. , Pirskanen‐Matell, R. , Heikkinen, A. , Oikarainen, T. , Risteli, J. and Pihlajaniemi, T. (2018), Autoimmune antibodies to collagen XIII in myasthenia gravis patients. Muscle Nerve, 57: 506-510, which has been published in final form at https://doi.org/10.1002/mus.25969. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
https://rightsstatements.org/vocab/InC/1.0/
https://urn.fi/URN:NBN:fi-fe201901031210
Tiivistelmä
Abstract
Introduction: Evaluation of the nerve fascicular structure can be useful in diagnosing nerve damage, but it is a very challenging task with 3T MRI because of limited resolution. In this pilot study, we present the feasibility of high‐resolution 7T MRI for examining the nerve fascicular structure.
Methods: A 3‐dimensional (3D) gradient‐spoiled sequence was used for imaging peripheral nerves in extremities. Images acquired with different in‐plane resolutions (0.42 × 0.42 mm vs. 0.12 × 0.12 mm), and different main field strengths (7T vs. 3T) were compared.
Results: The individual nerve fascicles were identified at 0.12 × 0.12 mm resolution in both field strengths but not at 0.42 × 0.42 mm resolution. The fascicular structure was more sharply depicted in 7T images than in 3T images.
Discussion: High‐resolution 3D imaging with 7T MRI demonstrated feasibility for imaging nerve fascicular structures.
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