iNEXT : a European facility network to stimulate translational structural biology

Abstract

<div lang="en" class="abs"><p class="abs_header">Abstract</p><p>iNEXT, ‘Infrastructure for NMR, EM and X‐rays for Translational research’, is a EC‐funded Horizon 2020 network of national infrastructures aiming to facilitate EC‐supported, trans‐national user access to several high‐end structural biology infrastructures and to expand the use of structural biology technologies towards new research communities. iNEXT has developed different access routes offering cutting edge technologies and expertise, thus targeting the diverse needs of research groups that desire to perform X‐ray crystallography, small‐angle X‐ray scattering, solution or solid‐state NMR, single particle or cell tomography electron microscopy, biophysics, and imaging experiments. Specific Joint Research Activities aim at improving the user experience in ever advancing methods, and are focused on structure‐based drug discovery, membrane protein characterization and structural cell biology initiatives.</p></div>

<div lang="en" class="abs"><p class="abs_header">iNEXT Consortium members</p><p>Rolf Boelens (Coordinator): Universiteit Utrecht, Utrecht, The Netherlands; Dmitri Svergun, Jan Ellenberg, Stephen Cusack: European Molecular Biology Laboratory (Hamburg, Heidelberg and Grenoble sites, respectively); Martin A. Walsh, Diamond Light Source Limited, Didcot, United Kingdom; Lucia Banci: Consorzio Interuniversitario Risonanze Magnetiche di Metallo Proteine, Firenze, Italy; Harald Schwalbe, Johann Wolfgang Goethe Universitaet, Frankfurt am Main, Germany; Anastassis Perrakis: Stichting het Nederlands Kanker Instituut ‐ Antoni van Leeuwenhoek Ziekenhuis, Amsterdam, The Netherlands; Vladimír Sklenář, Masarykova Univerzita, Brno, Czech Republic; Jose Maria Carazo Garcia: Agencia Estatal Consejo Superior de Investigaciones Cientificas, Madrid, Spain; Hartmut Oschkinat: Forschungsverbund Berlin E.V., Berlin, Germany; Andrew Thompson: Société Civile Synchrotron SOLEIL, Gif sur Yvette, France; Marjolein Thunnissen: Lunds Universitet, Lund, Sweden; Bram Koster: Universiteit Leiden and Leids Universitair Medisch Centrum, Leiden, The Netherlands; Gordon Leonard: Installation Europeenne de Rayonnement Synchrotron, Grenoble, France; Bernhard Brutscher: Centre National de la Recherche Scientifique, Grenoble/Lyon, France; David I. Stuart: INSTRUCT Academic Services Limited, Oxford, United Kingdom; Poul Nissen: Aarhus Universitet, Aarhus, Denmark; Hanna Wacklin: European Spallation Source ESS AB, Lund, Sweden; András Perczel: Eotvos Lorand Tudomanyegyetem, Budapest, Hungary; Margarida Archer: Instituto de Tecnologia Quimica e Biologica, Oeiras, Portugal; Rik Wierenga: Oulun Yliopisto, Oulu, Finland; Georgios A. Spyroulias: University of Patras, Rio Patras, Greece; Joel Sussman: Weizmann Institute of Science, Rehovot, Israel.</p></div>