Non‑curative treatment of patients with oral tongue squamous‑cell carcinoma
Mroueh, R.; Haapaniemi, A.; Saarto, T.; Grönholm, L.; Grénman, R.; Salo, T.; Mäkitie, A. A. (2019-05-08)
Mroueh, R., Haapaniemi, A., Saarto, T. et al. Eur Arch Otorhinolaryngol (2019) 276: 2039. https://doi.org/10.1007/s00405-019-05456-y
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https://creativecommons.org/licenses/by/4.0/
https://urn.fi/URN:NBN:fi-fe2019061220152
Tiivistelmä
Abstract
Purpose: Late-stage OTSCC is associated with poor overall survival (OS). Non-curative treatment approach aims to improve quality of life and prolong survival of patients deemed incurable. The purpose of this study was to investigate the used non-curative treatment modalities for OTSSC and patient survival.
Methods: All patients diagnosed with OTSCC and treated with non-curative intent at the HUS Helsinki University Hospital (Helsinki, Finland) during the 12-year period of 2005–2016 were included. Survival analysis after the non-curative treatment decision was conducted using the Kaplan–Meier method in this population-based study.
Results: Eighty-two patients were identified. A non-curative treatment decision was made at presentation without any previous treatment in 26 patients (7% of all patients diagnosed with OTSCC during the study period). Palliative radiotherapy was administered to 24% of all patients. The average survival time after the non-curative treatment decision was 3.7 months (median 2 and range 0–26).
Conclusions: Due to the short mean survival time after decision for treatment with non-curative intent, and the notable symptom burden in this patient population, a prompt initiation of all non-curative measures is warranted.
Kokoelmat
- Avoin saatavuus [34183]
