Hyperpolarized Laplace NMR
Telkki, Ville‐Veikko (2018-06-04)
Telkki V‐V. Hyperpolarized Laplace NMR. Magn Reson Chem. 2018;56:619–632. https://doi.org/10.1002/mrc.4722
© 2018 The Authors. Magnetic Resonance in Chemistry Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Laplace nuclear magnetic resonance (NMR), dealing with NMR relaxation and diffusion experiments, reveals details of molecular motion and provides chemical resolution complementary to NMR spectra. Laplace NMR has witnessed a great progress in past decades due to the development of methodology and signal processing, and it has lots of extremely interesting applications in various fields, including chemistry, biochemistry, geology, archaeology, and medicine. The aim of this minireview is to give a pedagogically oriented overview of Laplace NMR. It does not provide a full literature review of the field, but, instead, it elucidate the benefits and features of Laplace NMR methods through few selected examples. The minireview describes also recent progress in multidimensional Laplace NMR and Laplace inversion methods. Furthermore, the potential of modern hyperpolarization methods as well as ultrafast approach to increase the sensitivity and time‐efficiency of the Laplace NMR experiments is highlighted.
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