Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis
Huhtakangas, Johanna A.; Veijola, Johanna; Turunen, Sanna; Karjalainen, Anna; Valkealahti, Maarit; Nousiainen, Tomi; Yli-Luukko, Susanna; Vuolteenaho, Olli; Lehenkari, Petri (2017-04-29)
Johanna A. Huhtakangas, Johanna Veijola, Sanna Turunen, Anna Karjalainen, Maarit Valkealahti, Tomi Nousiainen, Susanna Yli-Luukko, Olli Vuolteenaho, Petri Lehenkari, Cytokine data obtained from synovial stromal cells of patients with rheumatoid arthritis or osteoarthritis, Data in Brief, Volume 12, 2017, Pages 593-602, ISSN 2352-3409, http://dx.doi.org/10.1016/j.dib.2017.04.041.
©2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license
https://creativecommons.org/licenses/by/4.0/
https://urn.fi/URN:NBN:fi-fe201708168133
Tiivistelmä
Abstract
In this article, we share the raw cytokine data obtained from basal and stimulated synovial stromal cells cultured from patients with rheumatoid arthritis or osteoarthritis. This data article is related to the research article entitled “1,25D₃ and calcipotriol, its hypocalcemic analog, exert a long-lasting anti-inflammatory and anti-proliferative effect in synoviocytes cultured from patients with rheumatoid arthritis and osteoarthritis (1). Cytokine levels were analyzed by a magnetic bead–based multiplex assay (a panel of 27 important cytokines) in two separate sets of experiments. The first was conducted with IL-1β and 1,25(OH)₂D₃ and the other with TNFα, calcipotriol, i.e. the hypocalcemic analog 1,25(OH)₂D₃, and dexamethasone. The raw data of this article display the individual variation in basal secretion of cytokines and in their response to different stimuli.
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