Vibrational spectroscopy of articular cartilage
Rieppo, Lassi; Töyräs, Juha; Saarakkala, Simo (2016-08-23)
Lassi Rieppo, Juha Töyräs & Simo Saarakkala (2017) Vibrational spectroscopy of articular cartilage, Applied Spectroscopy Reviews, 52:3, 249-266, DOI: 10.1080/05704928.2016.1226182
© 2016 Authors. Association of American Geographers© Lassi Rieppo, Juha Töyräs, and Simo Saarakkala This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Articular cartilage is a connective tissue that is located at the ends of long bones. Type II collagen, proteoglycans, water, and chondrocytes are the main constituents of articular cartilage. Osteoarthritis, the most common joint disease in the world, causes degenerative changes in articular cartilage tissue. Fourier transform infrared (FTIR), Raman, and near infrared (NIR) spectroscopic techniques offer versatile tools to assess biochemical composition and quality of articular cartilage. These vibrational spectroscopic techniques can be used to broaden our understanding about the compositional changes during osteoarthritis, and they also hold promise in disease diagnostics. In this article, the current literature of articular cartilage spectroscopic studies is reviewed.
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